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SHOW's R&D

From lab to patient:
New ideas for solutions demanded by the public!

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Basic research

  • Infectious Diseases

    • Periodontitis: Our core focus! In collaboration with 20 dental clinics in France.

    • Infectious diseases and diseases associated with periodontitis: A growing concern for us.

    • Lead researcher: Julien Santi-Rocca, PhD

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  • The patient and the healthcare system: Social Lab

    • Barriers to healthcare access and medical innovation

    • Prospective vision of the patient's role in healthcare decision-making: From the individual to public health policy.

    • Lead researcher: David F. Martín-García, PhD​

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Innovation

  • Diagnostics

    • AI-assisted microscopic microbiota analysis for health status quantification

  • Bioinformatics

    • Probabilistic and semantic taxonomic assignment method for sequencing reads (not protected, Paper in press in the Journal of Clinical Periodontology, Jan 2025)

  • Biochemistry

    • Universal eukaryotic microbiota sequencing with chemical blockers for contaminants (patent pending)

  • Synthetic Biology

    • Construction of homeobiotics: immune-activating probiotics aimed at maintaining homeostasis (ongoing projects)

  • Molecular Biology

    • Immediate multiplexed field diagnostics for infectious diseases and antibiotic resistance (ongoing projects)

Present... and future!

  • Our latest published paper:

  • Our latest accepted paper:

    • "Microbial complexes in subgingival plaque: a bacterial metataxonomic study" (01/25, in press, Journal of Clinical Periodontology)

  • Our papers in preparation:

    • "Microbial complexes in subgingival plaque: a eukaryotic metataxonomic study"

    • "Microbial types in subgingival plaque: a microscopic study"

  • Projects that we care about:

    • Access to diagnostics for women: new tools to break down old barriers

    • Peri-implant diseases and their microbiota

    • Animals and periodontal diseases: well-being, health, and prevention without species barriers

    • Oral diagnosis of diseases associated with periodontitis: a prognostic vision through early biomarkers and innovative tools​

    • Responsible dentistry and patient empowerment

    • Cultural and regulatory challenges in the rise of a new preventive medicine

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